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Productivity for free: Residence time gradients during loading increase dynamic binding capacity and productivity

  • Published:2022-01 Issue: Volume:281 Page:119985
  • ISSN:1383-5866
  • Container-title:Separation and Purification Technology
  • language:en
  • Short-container-title:Separation and Purification Technology

Author:

Eslami Touraj,Jakob Leo A.,Satzer Peter,Ebner Gerald,Jungbauer Alois,Lingg Nico

Funder

Horizon 2020 Marie Skłodowska-Curie Actions

Austrian Science Fund

FFG

Publisher

Elsevier BV

Subject

Filtration and Separation,Analytical Chemistry

Reference36 articles.

1. N.E. Labrou, Protein Purification: An Overview, in: 2014. https://doi.org/10.1007/978-1-62703-977-2_1.

2. Linear flow-velocity gradient chromatography—An efficient method for increasing the process efficiency of batch and continuous capture chromatography of proteins;Chen;Biotechnol. Bioeng.,2021

3. Separation science is the key to successful biopharmaceuticals;Guiochon;J. Chromatogr. A.,2011

4. FDA biopharmaceutical product approvals and trends in 2012;Rader;Bioprocess Int.,2013

5. Scale-up of twin-column periodic counter-current chromatography for mAb purification;Angelo;Bioprocess. Inter.,2018

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