The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53-Reference-Cited by-同舟云学术

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53

Published:2005-07 Issue:1 Volume:8 Page:75-87
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Higashitsuji Hiroaki,Higashitsuji Hisako,Itoh Katsuhiko,Sakurai Toshiharu,Nagao Toshikazu,Sumitomo Haruhiko,Masuda Tomoko,Dawson Simon,Shimada Yutaka,Mayer R. John,Fujita Jun

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference47 articles.

1. Regulation of p53 and MDM2 Activity by MTBP;Brady;Mol. Cell. Biol.,2005

2. A post-ubiquitination role for MDM2 and hHR23A in the p53 degradation pathway;Brignone;Oncogene,2004

3. Ubiquitination, phosphorylation and acetylation: The molecular basis for p53 regulation;Brooks;Curr. Opin. Cell Biol.,2003

4. Inhibiting the p53–MDM2 interaction: An important target for cancer therapy;Chene;Nat. Rev. Cancer,2003

5. Ubiquitin-mediated proteolysis: Biological regulation via destruction;Ciechanover;Bioessays,2000

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