Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency-Reference-Cited by-同舟云学术

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Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency

Published:2012-04 Issue:4 Volume:21 Page:547-562
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Wei Guo,Margolin Adam A.,Haery Leila,Brown Emily,Cucolo Lisa,Julian Bina,Shehata Shyemaa,Kung Andrew L.,Beroukhim Rameen,Golub Todd R.

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference45 articles.

1. The Bcl-2 apoptotic switch in cancer development and therapy;Adams;Oncogene,2007

2. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis;Adams;J. Biol. Chem.,2007

3. Reverse engineering of regulatory networks in human B cells;Basso;Nat. Genet.,2005

4. The landscape of somatic copy-number alteration across human cancers;Beroukhim;Nature,2010

5. Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance;Bewry;Mol. Cancer Ther.,2008

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