A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

Author:

Chauhan Dharminder,Catley Laurence,Li Guilan,Podar Klaus,Hideshima Teru,Velankar Mugdha,Mitsiades Constantine,Mitsiades Nicolas,Yasui Hiroshi,Letai Anthony,Ovaa Huib,Berkers Celia,Nicholson Benjamin,Chao Ta-Hsiang,Neuteboom Saskia T.C.,Richardson Paul,Palladino Michael A.,Anderson Kenneth C.

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference39 articles.

1. Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer;Adams;Curr. Opin. Chem. Biol.,2002

2. The proteasome: a suitable antineoplastic target;Adams;Nat. Rev. Cancer,2004

3. Proteasome inhibitors: a novel class of potent and effective antitumor agents;Adams;Cancer Res.,1999

4. Bortezomib therapy for myeloma;Anderson;Curr. Hematol. Rep.,2004

5. Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib;Berkers;Nat. Methods,2005

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