Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial

Author:

Fleischmann Roy,Mysler Eduardo,Hall Stephen,Kivitz Alan J,Moots Robert J,Luo Zhen,DeMasi Ryan,Soma Koshika,Zhang Richard,Takiya Liza,Tatulych Svitlana,Mojcik Christopher,Krishnaswami Sriram,Menon Sujatha,Smolen Josef S,Adams Luthando,Ally Mahmood M,du Plooy Maria C,Louw Ingrid C,Nayiager Savithree,Nel Christoffel B,Nel Debra,Reuter Helmuth,Soloman Ahmed S,Spargo Catherine E,Hall Stephen,Rischmueller Maureen,Sharma Shunil D,Will Robert K,Youssef Peter P,Arroyo Caroline,Baes Rosario P,Dulos Roger B,Hao Llewellyn T,Lanzon Allan E,Lichauco Juan Javier T,Mangubat Jill H,Ramiterre Edgar B,Reyes Bernadette Heizel M,Tan Perry P,Choe Jung-Yoon,Kang Young Mo,Kwon Seong Ryul,Lee Sang-Heon,Lee Shin-Seok,Yoo Dae-Hyun,Lin Hsiao-Yi,Luo Shue-Fen,Tsai Shih-Tzu,Tsai Wen-Chan,Tseng Jui-Cheng,Wei Cheng-Chung C,Asavatanabodee Paijit,Nantiruj Kanokrat,Nilganuwong Surasak,Uea-Areewongsa Parichat,Majstorovic Ljubinka Bozic,Bacic Suada Mulic,Batalov Anastas Z,Georgieva-Slavcheva Gabriela,Mihailova Mariyana,Nikolov Nikolay G,Penev Dimitar P,Spasov Yuliy A,Stanimirova Krasimira,Todorov Stoyan,Toncheva Antoaneta R,Yordanova Nadezhda,Mosterova Zdenka,Novosad Libor,Prochazkova Leona,Stehlikova Helena,Stejfova Zuzana,Kiseleva Natalia,Pank Lea,Savi Triin,Alexandra Balbir-Gurman,Amital Howard,Mevorach Dror,Rosner Itzhak A,Mihailova Anna,Stumbra-Stumberga Evija,Basijokiene Vida,Lietuvininkiene Virginija,Unikiene Dalia,Brzezicki Jan,Dudek Anna M,Glowacka-Kulesz Maria B,Grabowicz-Wasko Barbara,Hajduk-Kubacka Sabina,Hilt Joanna,Hrycaj Pawel,Jeka Slawomir,Kolasa Renata,Krogulec Marek,Mastalerz Hanna,Olak-Popko Anna,Owczarek Elzbieta,Ruzga Zofia,Walczak Alina,Ancuta Codrina I,Ancuta Ioan,Balanescu Andra R,Berghea Florian,Bojin Silvia,Arvunescu Mihaela A Ianuli,Ionescu Ruxandra M,Mociran Eugenia,Pavel Mariana,Rednic Simona,Voie Adriana,Zainea Carmen M,Bugrova Olga V,Demin Alexander,Ershova Olga B,Gavrisheva Inna A,Krechikova Diana G,Kuropatkin Gennady V,Marusenko Irina M,Menshikova Irina V,Noskov Sergey M,Rebrov Andrey P,Smakotina Svetlana A,Yakushin Sergey S,Zhilyaev Evgeny,Ramos Juan Jose Amarelo,Garcia Francisco Javier Blanco,Nebro Antonio Fernandez,Esteban Silvia Perez,Burson Juan Miguel Sanchez,Sala Raimon Sanmarti,Ataman Sebnem,Hizmetli Sami,Kuru Omer,Douglas Karen M,Emery Paul,Moots Robert J,Ong Voon H,Sheeran Thomas P,Faraawi Rafat Y,Lessard Clode,Mendoza Carlos Abud,Avila-Armengol Hilario Ernesto,Zapata Francisco I Avila,Irazoque-Palazuelos Fedra Consuelo,Cecena Marco Antonio Maradiaga,Pacheco-Tena Cesar F,Rizo-Rodriguez Juan C,Rodriguez-Torres Isaura M,Aelion Jacob A,Caciolo Barbara A,Calmes James M,Chatpar Prem,Dayal Nimesh,De Jesus Alex,Dikranian Ara H,Diri Erdal,Fairfax Michael J,Fenton Ira F,Fleischmann Roy M,Gaylis Norman B,George Ronald L,Halter Dale G,Hernandez Paul,Hole Susan A,Hou Antony C,Huff John P,Kafaja Suzanne,Kennedy Alastair C,Kenney Howard,Kimmel Steven C,Kirby Brian S,Kivitz Alan J,Legerton Clarence W,Lindsey Stephen M,Mallepalli Jyothi R,Mathews Steven D,Metyas Samy K,Mizutani Wesley T,Najam Sabeen,Nascimento Joao M,Pang Shirley W,Patel Rakesh C,Poiley Jeffrey E,Ramirez Carlos E,Reddy Riteesha,Rehman Qaiser,Schnitz William M,Scoville Craig D,Shergy William J,Silverfield Joel C,Singhal Atul K,Smallwood-Sherrer Yvonne R,Songcharoen Suthin N,Stack Michael T,Stohl William,Su Tien-I K,Udell James,Waraich Saleem,Weidmann Charles E,Wei Nathan,Wiesenhutter Craig W,Winkler Anne E,Zagar Karen E,Berman Alberto,Mysler Eduardo F,Hidalgo Rodolfo A Pardo,Venarotti Horacio O,Sariego Irmgadt Annelise Goecke,Calabresse Renato E Jimenez,Ruiz-Tagle Juan Ignacio Vargas,Vargas Luis Fernando M Bellatin,Berrocal Alfredo E,Portocarrero Manuel Gustavo Leon,Jesus Felix,Pena Romero

Publisher

Elsevier BV

Subject

General Medicine

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