[ 3 H]L-655,708, a Novel Ligand Selective for the Benzodiazepine Site of GABA A Receptors which Contain the α5 Subunit-Reference-Cited by-同舟云学术

[ 3 H]L-655,708, a Novel Ligand Selective for the Benzodiazepine Site of GABA A Receptors which Contain the α5 Subunit

Published:1996 Issue:9-10 Volume:35 Page:1331-1335
ISSN:0028-3908
Container-title:Neuropharmacology
language:en
Short-container-title:Neuropharmacology

Author:

QUIRK K.,BLURTON P.,FLETCHER S.,LEESON P.,TANG F.,MELLILO D.,RAGAN C.I.,MCKERNAN R.M.

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference16 articles.

1. High affinity [3H]zolpidem binding in rat brain: an imidazopyridine with agonist properties at central benzodiazepine receptors;Arbilla;Eur. J. Pharmacol.,1986

2. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction;Cheng;Biochem. Pharmacol.,1973

3. Substitution at position 8 of imidazo-benzodiazepine-6-ones is a determinant for GABAA α5-subtype selectivity;Gillard;Br. J. Pharmacol.,1994

4. Cloning of cDNA sequences encoding the α2 and α3 GABAA receptor subunits and characterisation of the benzodiazepine pharmacology of recombinant α1-, α2-, α3- and α5-containing human GABAA receptors;Hadingham;Mol. Pharmacol.,1993

5. GABAA receptors immunopurified from rat brain with α-subunit specific antibodies have unique pharmacological properties;McKernan;Neuron,1991

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