Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an α5-GABAA receptor NAM-Reference-Cited by-同舟云学术

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Novel imidazo[1,5-a]quinoxaline derivatives: SAR, selectivity and modeling challenges en route to the identification of an α5-GABAA receptor NAM

Published:2023-01 Issue: Volume:80 Page:129107
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Károlyi Benedek Imre,Potor Attila,Kapus Gábor László,Fodor László,Bobok Amrita,Krámos Balázs,Magdó Ildikó,Bata Imre,Szabó György

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. GABAA receptor channels;Macdonald;Annu Rev Neurosci,1994

2. Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors;Farrant;Nat Rev Neurosci,2005

3. GABAA receptors: subtypes provide diversity of function and pharmacology;Olsen;Neuropharm,2008

4. The potential use of GABA agonists in psychiatric disorders: evidence from studies with progabide in animal models and clinical trials;Lloyd;Pharmacol Biochem Behav,1983

5. Midazolam: pharmacology and uses;Reves;Anesthesiology,1985

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