Breast cancer cells are sensitized by piperine to radiotherapy through estrogen receptor-α mediated modulation of a key NHEJ repair protein- DNA-PK

Author:

Shaheer Koniyan,Prabhu BR Swathi,Ali H. Shabeer,Lakshmanan-M Divya

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference89 articles.

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2. Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update;Allison;J. Clin. Oncol.,2020

3. Estrogen receptor α L543A,L544A mutation changes antagonists to agonists, correlating with the ligand binding domain dimerization associated with DNA binding activity;Arao;J. Biol. Chem.,2013

4. Enhanced phosphorylation of p53 by ATM in response to DNA damage;Banin;Science (80-.),1998

5. H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ;Bayley;Mol. Cell,2022

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