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Stigmasterol can be new steroidal drug for neurological disorders: Evidence of the GABAergic mechanism via receptor modulation

  • Published:2021-09 Issue: Volume:90 Page:153646
  • ISSN:0944-7113
  • Container-title:Phytomedicine
  • language:en
  • Short-container-title:Phytomedicine

Author:

Karim Nasiara,Khan Imran,Abdelhalim Abeer,Halim Sobia Ahsan,Khan Ajmal,Al-Harrasi Ahmed

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference62 articles.

1. Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis;Agis-Balboa;Proc. Natl. Acad. Sci. U.S.A.,2006

2. Mechanisms of neurosteroid interactions with GABA(A) receptors;Akk;Pharmacol. Ther.,2007

3. Phytosterols, phytostanols and their esters: from natural to functional foods;Bacchetti;Med. J. Nutrit. Metab.,2011

4. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor;Belelli;Neurobiol. Stress,2020

5. Neurosteroids: endogenous regulators of the GABAA receptor;Belelli;Nat. Rev. Neurosci.,2005
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