Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels-Reference-Cited by-同舟云学术

Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels

Published:2020-07 Issue: Volume:511 Page:110835
ISSN:0303-7207
Container-title:Molecular and Cellular Endocrinology
language:en
Short-container-title:Molecular and Cellular Endocrinology

Author:

Lindqvist A.,Shcherbina L.,Prasad R.B.,Miskelly M.G.,Abels M.,Martínez-Lopéz J.A.,Fred R.G.,Nergård B.J.,Hedenbro J.,Groop L.,Hjerling-Leffler J.,Wierup N.

Funder

Stiftelsen för Strategisk Forskning

Vetenskapsrådet

Publisher

Elsevier BV

Subject

Endocrinology,Molecular Biology,Biochemistry

Reference24 articles.

1. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans;Ariyasu;J. Clin. Endocrinol. Metab.,2001

2. Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents;Dezaki;Diabetes,2004

3. Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin;Dezaki;Diabetes,2007

4. Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis;Dezaki;Pharmacol. Ther.,2008

5. A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control;Dornonville de la Cour;Regul. Pept.,2001

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