Clinical applications of small molecule inhibitors of Pregnane X receptor
Author:
Funder
Kansas City University of Medicine and Biosciences
Publisher
Elsevier BV
Subject
Endocrinology,Molecular Biology,Biochemistry
Reference108 articles.
1. Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action;Aune;Anti Canccer Drugs,2002
2. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism;Bhalla;J. Biol. Chem.,2004
3. Coumestrol, a new estrogen isolated from forage crops;Bickoff;Science,1957
4. Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms;Bitter;Arch. Toxicol.,2015
5. Exploration of the conformational landscape in pregnane X receptor reveals a new binding pocket;Chandran;Protein Sci.,2016
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pregnane X Receptor Signaling Pathway and Vitamin K: Molecular Mechanisms and Clinical Relevance in Human Health;Cells;2024-04-14
2. UCP1 activation: Hottest target in the thermogenesis pathway to treat obesity using molecules of synthetic and natural origin;Drug Discovery Today;2023-09
3. Gefitinib Inhibits Rifampicin-Induced CYP3A4 Gene Expression in Human Hepatocytes;ACS Omega;2022-09-13
4. Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in Male and Female Mice Genetically Predisposed to Alzheimer’s Disease;Drug Metabolism and Disposition;2022-07-25
5. Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library;Cells;2022-04-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3