Novel donepezil-like N -benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine “bio-oxidizable” prodrugs: Synthesis, biological evaluation and structure-activity relationship-Reference-Cited by-同舟云学术

Novel donepezil-like N -benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine “bio-oxidizable” prodrugs: Synthesis, biological evaluation and structure-activity relationship

Published:2018-02 Issue: Volume:145 Page:165-190
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Azzouz Rabah,Peauger Ludovic,Gembus Vincent^ORCID,Ţînţaş Mihaela-Liliana,Sopková-de Oliveira Santos Jana,Papamicaël Cyril,Levacher Vincent

Funder

INSA-Rouen

Rouen University

CNRS

Labex SynOrg

Région Haute-Normandie

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference80 articles.

1. 2014 Alzheimer's disease facts and figures

2. 2015 Alzheimer's disease facts and figures;Alzheimer's Association;Alzheimer's Dementia,2015

3. Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer's disease;Kar;J. Psychiatr. Neurosci.,2004

4. Neutrophic factors in Alzheimer's disease: role of axonal transport;Schindowski;Gene Brain Behav.,2008

5. Neuropathological alterations in Alzheimer disease;Serrano-Pozo;Cold Spring Harbor Perspect. Med.,2011

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of 4-Alkylated 1,4-Dihydropyridines: Fe(II)-Mediated Oxidative Cascade Cyclization Reaction of Cyclic Ethers with Enaminones;The Journal of Organic Chemistry;2023-08-09

2. Chalcones bearing nitrogen‐containing heterocyclics as multi‐targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies;Journal of Molecular Recognition;2023-05-05

3. Fe-mediated oxidative cascade [1 + 2 + 3]-cyclization/esterification reaction: synthesis of 4-alkylated 1,4-dihydropyridines;Organic & Biomolecular Chemistry;2023

4. Roles of hybrid donepezil scaffolds as potent human acetylcholinesterase inhibitors using in silico interaction analysis, drug-likeness, and pharmacokinetics prediction;Chemico-Biological Interactions;2022-12

5. Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment;Bioorganic Chemistry;2022-12