The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity
Author:
Funder
National Institutes of Health
Wayne State University
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference63 articles.
1. Protein posttranslational modifications: the chemistry of proteome diversifications;Walsh;Angew. Chem. Int. Ed.,2005
2. A direct link between core histone acetylation and transcriptionally active chromatin;Hebbes;EMBO J.,1988
3. LSD1 substrate binding and gene expression are affected by HDAC1-mediated deacetylation;Nalawansha;ACS Chem. Biol.,2017
4. HDAC inhibitor-induced mitotic arrest is mediated by Eg5/KIF11 acetylation;Nalawansha;Cell Chem. Biol.,2017
5. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis;Gregoretti;J. Mol. Biol.,2004
Cited by 38 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Advances in dual-targeting inhibitors of HDAC6 for cancer treatment;European Journal of Medicinal Chemistry;2024-09
2. Genetic and epigenetic alterations in human cancers;Biopolymers and Cell;2024-03-20
3. Targeting Histone Deacetylases 6 in Dual-Target Therapy of Cancer;Pharmaceutics;2023-11-03
4. Targeting histone deacetylases for cancer therapy: Trends and challenges;Acta Pharmaceutica Sinica B;2023-06
5. Hydroxamic acid derivatives as selective HDAC3 inhibitors: computer-aided drug design strategies;Journal of Biomolecular Structure and Dynamics;2023-03-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3