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Antibody-drug conjugates of 7-ethyl-10-hydroxycamptothecin: Sacituzumab govitecan and labetuzumab govitecan

  • Published:2019-04 Issue: Volume:167 Page:583-593
  • ISSN:0223-5234
  • Container-title:European Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:European Journal of Medicinal Chemistry

Author:

Dong Wenjuan,Shi Jianyou,Yuan Ting,Qi Baowen,Yu Jiying,Dai Jingying,He LinORCID

Funder

International Cooperation and Exchange Program of Science and Technology Department of Sichuan Province

Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital Youth Talent Fund

University of Electronic Science and Technology of China Central University Basic Research Expenses Project

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference93 articles.

1. Antibody-drug conjugates in cancer therapy;Sievers;Annu. Rev. Med.,2013

2. Antibody–drug conjugates as novel anti-cancer chemotherapeutics;Christina;Biosci. Rep.,2015

3. Antibody–drug conjugates: an emerging concept in cancer therapy;Chari;Angew. Chem. Int. Ed.,2014

4. Paul Ehrlich's magic bullet concept: 100 years of progress;Strebhardt;Nat. Rev. Canc.,2008

5. Improving the therapeutic index in cancer therapy by using antibody-drug conjugates designed with a moderately-cytotoxic drug;Govindan;Mol. Pharm.,2015

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