Improving the Therapeutic Index in Cancer Therapy by Using Antibody–Drug Conjugates Designed with a Moderately Cytotoxic Drug
Author:
Affiliation:
1. Immunomedics, Inc., Morris Plains, New Jersey 07950, United States
2. Center for Molecular Medicine and Immunology, Morris Plains, New Jersey 07950, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp5006195
Reference56 articles.
1. Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer
2. Brentuximab vedotin
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4. Antibody−Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies
5. Antibody-Drug Conjugates in Cancer Therapy
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