Mechanism-based design, synthesis and biological studies of N5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents-Reference-Cited by-同舟云学术

Mechanism-based design, synthesis and biological studies of N5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents

Published:2012-12 Issue: Volume:58 Page:228-236
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zhang Zhili,Tian Chao,Zhou Shouxin,Wang Wei,Guo Ying,Xia Jie,Liu Zhenming,Wang Biao,Wang Xiaowei,Golding Bernard T.,Griff Roger J.,Du Yansheng,Liu Junyi

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference27 articles.

1. Providing one-carbon units for biological methylations: mechanistic studies on serine hydroxymethyltransferase, methylenetetrahydrofolate reductase, and methyltetrahydrofolate-homocysteine methyltransferase

2. Stereochemical analysis of the methyl transfer catalyzed by cobalamin-dependent methionine synthase from Escherichia coli B

3. B12 Trafficking in Mammals: A Case for Coenzyme Escort Service

4. Reactions of cobalt(I) supernucleophiles. The alkylation of vitamin B12s, cobaloximes(I), and related compounds

5. Cobalamin‐dependent methionine synthase

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