The phenolic metabolites of the anti-HIV drug efavirenz: Evidence for distinct reactivities upon oxidation with Frémy's salt

Author:

Harjivan Shrika G.,Wanke Riccardo,Ferreira da Silva João L.,Marques M. Matilde,Antunes Alexandra M.M.ORCID

Funder

Fundação para a Ciência e a Tecnologia (FCT), Portugal

Centro de Química Estrutural

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference29 articles.

1. Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society – USA panel;Thompson;J. Am. Med. Assoc.,2010

2. Long-term assessment of neuropsychiatric adverse reactions associated with efavirenz;Lochet;HIV Med.,2003

3. Implications of efavirenz for neuropsychiatry: a review;Cavalcante;Int. J. Neurosci.,2010

4. Is it safe to switch between efavirenz and nevirapine in the event of toxicity?;Mehta;Lancet Infect. Dis.,2007

5. Insights into the role of bioactivation mechanisms in the toxic events elicited by non-nucleoside reverse transcriptase inhibitors;Pereira,2012

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