Efavirenz exposure, alone and in combination with known drugs of abuse, engenders addictive-like bio-behavioural changes in rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-29978-3.pdf
Reference83 articles.
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3. Marzolini, C. et al. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS 15, 71–75 (2001).
4. Kryst, J., Kawalec, P. & Pilc, A. Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: a systematic review and meta-analysis of randomized controlled trials. PloS one 10, e0124279 (2015).
5. Almond, L. M., Hoggard, P. G., Edirisinghe, D., Khoo, S. H. & Back, D. J. Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals. J. Antimicrob. Chemother. 56, 738–744 (2005).
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