Synthesis and in vitro activity of novel N-3 acylated TSAO-T compounds against HIV-1 and HCV-Reference-Cited by-同舟云学术

Synthesis and in vitro activity of novel N-3 acylated TSAO-T compounds against HIV-1 and HCV

Published:2011-10 Issue:10 Volume:46 Page:5046-5056
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Moura Marina,Josse Solen,Van Nhien Albert Nguyen,Fournier Carole,Duverlie Gilles,Castelain Sandrine,Soriano Elena,Marco-Contelles José,Balzarini Jan,Postel Denis

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

1. 3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-.beta.-D-xylo- and -ribofuranose]-3'-spiro-5''-[4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide] (TSAO) pyrimidine nucleosides

2. Synthesis of {1-[2′,5′-bis-O-(tert-butyldimethylsilyl)-β-D-xylo- and β-D-ribofuranosyl]thymine}-3′-spiro-5′-{4′-amino-1′,2′-oxathiole 2′,2′-dioxide} (TSAO). A novel type of specific anti-HIV agents;Perez-Perez;Tetrahedron Lett.,1992

3. 2′,5′-Bis-O-(tert-butyldimethylsilyl)-3′-spiro-5′-(4′-amino-1′,2′-oxathiole-2′,2′-dioxide)pyrimidine (TSAO) nucleoside analogs: highly selective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase;Balzarini;Proc. Natl. Acad. Sci. U. S. A.,1992

4. HIV-1 specific reverse transcriptase inhibitors: why are TSAO-nucleosides so unique?;Camarasa;J. Carbohydr. Chem.,2000

5. TSAO compounds: the comprehensive story of a unique family of HIV-1 specific inhibitors of reverse transcriptase;Camarasa;Curr. Top. Med. Chem. (Sharjah, United Arab Emirates),2004

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