Discovery of novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors for the efficient treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo

Author:

Li Yanchun,Yang Huali,Zhao Xiangling,Zhao Xianchen,Quan Jishun,Wang Lei,Ma Enlong,Ma Chao

Publisher

Elsevier BV

Reference27 articles.

1. Idiopathic pulmonary fibrosis;Richeldi;Lancet,2017

2. Harnessing the role of HDAC6 in idiopathic pulmonary fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors;Campiani;J. Med. Chem.,2021

3. The epidemiology of idiopathic pulmonary fibrosis and interstitial lung diseases at risk of a progressive-fibrosing phenotype;Amy;Eur. Respir. Rev.,2018

4. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy;Selman;Ann. Intern. Med.,2001

5. Emerging therapeutic interventions for idiopathic pulmonary fibrosis;Chakraborty;Expet Opin. Invest. Drugs,2014

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