Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists-Reference-Cited by-同舟云学术

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Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists

Published:2017-01 Issue: Volume:125 Page:586-602
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Alachouzos Georgios,Lenselink Eelke B.,Mulder-Krieger Thea,de Vries Henk,IJzerman Adriaan P.,Louvel Julien

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference46 articles.

1. International union of basic and clinical pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update;Fredholm;Pharmacol. Rev.,2011

2. Adenosine receptors as therapeutic targets;Jacobson;Nat. Rev. Drug Disc.,2006

3. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs;Fredholm;Annu. Rev. Pharmacol. Toxicol.,2005

4. A1 receptors ligands: past, present and future trends;Schenone;Curr. Top. Med. Chem.,2010

5. Discovery of 1,2,4-triazine derivatives as adenosine A2A antagonists using structure based drug design;Congreve;J. Med. Chem.,2012

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