Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase-Reference-Cited by-同舟云学术

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Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

Published:2012-01 Issue: Volume:47 Page:493-500
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

van Linden Oscar P.J.,Farenc Carine,Zoutman Willem H.,Hameetman Liesbeth,Wijtmans Maikel,Leurs Rob,Tensen Cornelis P.,Siegal Gregg,de Esch Iwan J.P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. Eph-ephrin bidirectional signaling in physiology and disease;Pasquale;Cell,2008

2. Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling;Himanen;Nat. Neurosci.,2004

3. Mechanisms and functions of Eph and ephrin signalling;Kullander;Nat. Rev. Mol. Cell Biol.,2002

4. Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sezary syndrome identified by gene expression analysis;van Doorn;Cancer Res.,2004

5. EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth;Iiizumi;Cancer Sci.,2006

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