First-in-class allosteric inhibitors of bacterial IMPDHs-Reference-Cited by-同舟云学术

First-in-class allosteric inhibitors of bacterial IMPDHs

Published:2019-04 Issue: Volume:167 Page:124-132
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Alexandre Thomas,Lupan Alexandru,Helynck Olivier,Vichier-Guerre Sophie,Dugué Laurence,Gelin Muriel,Haouz Ahmed^ORCID,Labesse Gilles,Munier-Lehmann Hélène^ORCID

Funder

Centre National de la Recherche Scientifique

nstitut National de la Santé Et de la Recherche Médicale

Institut Pasteur, the Conseil Régional d'Ile-de-France

French Infrastructure for Integrated Structural Biology

Conseil Régional d'Ile-de-France

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

1. The structure of a domain common to archaebacteria and the homocystinuria disease protein;Bateman;Trends Biochem. Sci.,1997

2. Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid;Sintchak;Cell,1996

3. CBS domains: ligand binding sites and conformational variability;Ereño-Orbea;Arch. Biochem. Biophys.,2013

4. CBS domains: structure, function, and pathology in human proteins;Ignoul;Am. J. Physiol. Cell Physiol.,2005

5. CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations;Scott;J. Clin. Invest.,2004

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