Development of bioactive gemcitabine-D-Lys6-GnRH prodrugs with linker-controllable drug release rate and enhanced biopharmaceutical profile-Reference-Cited by-同舟云学术

Development of bioactive gemcitabine-D-Lys6-GnRH prodrugs with linker-controllable drug release rate and enhanced biopharmaceutical profile

Published:2019-03 Issue: Volume:166 Page:256-266
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sayyad Nisar,Vrettos Eirinaios I.,Karampelas Theodoros,Chatzigiannis Christos M.,Spyridaki Katerina,Liapakis George,Tamvakopoulos Constantin,Tzakos Andreas G.^ORCID

Funder

ESF

ARISTEIA II

MIS

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference44 articles.

1. Novel delivery approaches for cancer therapeutics;Mitra;J. Contr. Release,2015

2. Peptide-drug conjugate GnRH-sunitinib targets angiogenesis selectively at the site of action to inhibit tumor growth;Argyros;Cancer Res.,2016

3. GnRH-Gemcitabine conjugates for the treatment of androgen-independent prostate cancer: pharmacokinetic enhancements combined with targeted drug delivery;Karampelas;Bioconjug. Chem.,2014

4. On the design principles of peptide-drug conjugates for targeted drug delivery to the malignant tumor site;Vrettos;Beilstein J. Org. Chem.,2018

5. Development of a novel conjugatable sunitinib analogue validated through in vitro and in vivo preclinical settings;El Mubarak;J. Chromatogr. B, Anal. Technol. Biomed. Life Sci.,2018

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