GnRH-Gemcitabine Conjugates for the Treatment of Androgen-Independent Prostate Cancer: Pharmacokinetic Enhancements Combined with Targeted Drug Delivery

Author:

Karampelas Theodoros1,Argyros Orestis1,Sayyad Nisar,Spyridaki Katerina2,Pappas Charalampos,Morgan Kevin3,Kolios George4,Millar Robert P567,Liapakis George2,Tzakos Andreas G.,Fokas Demosthenes,Tamvakopoulos Constantin1

Affiliation:

1. Division of Pharmacology-Pharmacotechnology, Biomedical Research Foundation of the Academy of Athens, Soranou Ephessiou Street 4, Athens GR-11527, Greece

2. Department of Pharmacology, Faculty of Medicine, University of Crete, Heraklion, Crete, GR-71003, Greece

3. Respiratory Medicine, Castle Hill Hospital, Hull York Medical School, University of Hull, Hull, Yorkshire HU6 7RX, United Kingdom

4. Laboratory of Pharmacology, School of Medicine, Democritus University of Thrace, Alexandroupolis, GR-68100, Greece

5. Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa

6. UCT/MRC Receptor Biology Group, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

7. Centre for Integrative Medicine, University of Edinburgh, Edinburgh EH8 9YL, Scotland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

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