1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Author:

Legru Alice,Verdirosa Federica,Hernandez Jean-François,Tassone GiusyORCID,Sannio Filomena,Benvenuti ManuelaORCID,Conde Pierre-Alexis,Bossis GuillaumeORCID,Thomas Caitlyn A.ORCID,Crowder Michael W.,Dillenberger Melissa,Becker Katja,Pozzi CeciliaORCID,Mangani StefanoORCID,Docquier Jean-DenisORCID,Gavara LaurentORCID

Funder

Deutsche Forschungsgemeinschaft

Agence nationale de la recherche

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference67 articles.

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3. Burden of AMR Collaborative Group. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis;Cassini;Lancet Infect. Dis.,2019

4. Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery and Development of New Antibiotics;World Health Organization,2017

5. The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response;Walsh;J. Antimicrob. Chemother.,2012

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