Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect

Author:

Abatematteo Francesca S.ORCID,Mosier Philip D.,Niso MauroORCID,Brunetti LeonardoORCID,Berardi Francesco,Loiodice FulvioORCID,Contino Marialessandra,Delprat BenjaminORCID,Maurice TanguiORCID,Laghezza AntonioORCID,Abate CarmenORCID

Funder

Université de Montpellier

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference56 articles.

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2. Cloning the Sigma2 receptor: wandering 40 Years to find an identity;Kim;Proc. Natl. Acad. Sci. U. S. A,2017

3. Purification, molecular cloning, and expression of the mammalian sigma1-binding site;Hanner;Proc. Natl. Acad. Sci. U. S. A,1996

4. Crystal structure of the human σ1 receptor;Schmidt;Nature,2016

5. Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site;Xu;Nat. Commun.,2011

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