Design and synthesis of Mannich base-type derivatives containing imidazole and benzimidazole as lead compounds for drug discovery in Chagas Disease-Reference-Cited by-同舟云学术

Design and synthesis of Mannich base-type derivatives containing imidazole and benzimidazole as lead compounds for drug discovery in Chagas Disease

Published:2021-11 Issue: Volume:223 Page:113646
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Beltran-Hortelano Iván,Atherton Richard L.^ORCID,Rubio-Hernández Mercedes,Sanz-Serrano Julen^ORCID,Alcolea Verónica,Kelly John M.^ORCID,Pérez-Silanes Silvia,Olmo Francisco^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

1. Chagas' disease;Bern;N. Engl. J. Med.,2015

2. Current drug therapy and pharmaceutical challenges for Chagas disease;Bermudez;Acta Trop.,2016

3. Challenge in Chagas disease drug discovery: a review;Paucar;Curr. Med. Chem.,2016

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular targets for Chagas disease: validation, challenges and lead compounds for widely exploited targets;Expert Opinion on Therapeutic Targets;2023-10-03

2. Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design;Current Topics in Medicinal Chemistry;2023-10

3. Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose;Journal of Medicinal Chemistry;2023-09-18

4. Cu(II)-Catalyzed Cascade of N-Phenyl-o-phenylenediamine with Benzaldehyde: One-Step Direct Construction of 2-(1-Phenyl-1H-benzo[d]imidazol-2-yl)phenols;The Journal of Organic Chemistry;2023-06-01

5. (Benz)imidazoles;Privileged Scaffolds in Drug Discovery;2023