Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer-Reference-Cited by-同舟云学术

Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer

Published:2021-11 Issue: Volume:224 Page:113686
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Simov Vladimir^ORCID,Altman Michael D.,Bianchi Elisabetta,DelRizzo Sonia^ORCID,DiNunzio Edward N.,Feng Guo,Goldenblatt Peter^ORCID,Ingenito Raffaele^ORCID,Johnson Scott A.,Mansueto My Sam,Mayhood Todd,Mortison Jonathan D.,Serebrov Victor,Sondey Christopher^ORCID,Sriraman Venkat,Tucker Thomas J.,Walji Abbas,Wan Hui,Yue Yingzi,Stoeck Alexander,DiMauro Erin F.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference46 articles.

1. KEAP1/NRF2 pathway in the frontiers of cancer and non-cancer cell metabolism;Chartoumpekis;Biochem. Soc. Trans.,2015

2. NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer;Hayes;Trends Biochem. Sci.,2009

3. Characterization of KEAP1-NRF2 genomic alterations across diverse tumor types: Co-occurring alterations, survival outcomes, and implications for targeting cancer metabolism;Sen;J. Clin. Oncol.,2018

4. Loss-of-function mutations in KEAP1 drive lung cancer progression via KEAP1/NRF2 pathway activation;Gong;Cell Commun. Signal.,2020

5. Nrf2 mediates metabolic reprogramming in Non-Small cell lung cancer;Zhao;Frontiers in Oncology,2020

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