Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity-Reference-Cited by-同舟云学术

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Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity

Published:2021-11 Issue: Volume:223 Page:113668
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Pflégr Václav,Horváth Lilla,Stolaříková Jiřina,Pál Adrián,Korduláková Jana,Bősze Szilvia,Vinšová Jarmila,Krátký Martin

Funder

ERDF

National Research Development and Innovation Office

Charles University

Grantová agentura České republiky

Slovak Research and Development Agency

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference26 articles.

1. Facile synthesis and antimycobacterial activity of isoniazid, pyrazinamide and ciprofloxacin derivatives;R Alsayed;Chem. Biol. Drug Des.,2021

2. New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: synthesis, antimycobacterial activity and investigation of their mechanism of action;Vosátka;Eur. J. Med. Chem.,2018

3. New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: higher potency and lower hepatocytotoxicity;Castelo-Branco;Eur. J. Med. Chem.,2018

4. New isoniazid derivatives with improved pharmaco-toxicological profile: obtaining, characterization and biological evaluation;Dragostin;Eur. J. Pharm. Sci.,2019

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1. Design, synthesis and docking studies of new molecular hybrids bearing benzimidazole and thiazolidine-2,4-dione as potential antitubercular agents;Journal of the Indian Chemical Society;2024-10

2. Hydrazide–Hydrazones as Potential Antitubercular Agents: An Overview of the Literature (1999–2023);SynOpen;2024-07-16

3. Unlocking InhA: Novel approaches to inhibit Mycobacterium tuberculosis;Bioorganic Chemistry;2024-05

4. Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA;European Journal of Medicinal Chemistry;2023-11

5. Halogenated Antimicrobial Agents to Combat Drug-Resistant Pathogens;Pharmacological Reviews;2023-10-16

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