New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower hepatocytotoxicity

Author:

Castelo-Branco Frederico Silva,de Lima Evanoel CrizantoORCID,Domingos Jorge Luiz de Oliveira,Pinto Angelo C.,Lourenço Maria Cristina S.,Gomes Karen Machado,Costa-Lima Mariana Marques,Araujo-Lima Carlos Fernando,Aiub Claudia Alessandra Fortes,Felzenszwalb IsraelORCID,Costa Thadeu Estevam M.M.,Penido Carmen,Henriques Maria G.,Boechat NubiaORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference50 articles.

1. World Health Organization (WHO) – Global Tuberculosis Report 2016. Available at http://apps.who.int/iris/bitstream/10665/250441/1/9789241565394-eng.pdf?ua=1.

2. Tuberculosis control: past 10 years and future progress;Frieden;Tuberculosis (Edinb),2003

3. Chemotherapy and diagnosis of tuberculosis;Saltini;Respir. Physiol.,2006

4. An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds;Branco;Curr. Top. Med. Chem.,2013

5. The mechanism of isoniazid killing: clarity through the scope of genetics;Vilchèze;Annu. Rev. Microbiol.,2007

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