Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity-Reference-Cited by-同舟云学术

Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity

Published:2022-01 Issue: Volume:228 Page:114036
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Li Zhanhui,Hao Yongjin,Yang Chengkui^ORCID,Yang Qing,Wu Shuwei,Ma Haikuo,Tian Sheng,Lu Haohao^ORCID,Wang Jingrui^ORCID,Yang Tao,He Sudan^ORCID,Zhang Xiaohu^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference38 articles.

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2. Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice;Berger;J. Immunol.,2014

3. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation;Cho;Cell,2009

4. RIP kinases as modulators of inflammation and immunity;He;Nat. Immunol.,2018

5. Necroptosis: a specialized pathway of programmed necrosis;Galluzzi;Cell,2008

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