Identification of novel short chain 4-substituted indoles as potent αvβ3 antagonist using structure-based drug design-Reference-Cited by-同舟云学术

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Identification of novel short chain 4-substituted indoles as potent αvβ3 antagonist using structure-based drug design

Published:2007-03 Issue:3 Volume:42 Page:334-343
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Raboisson Pierre,DesJarlais Renee L.,Reed Rolanda,Lattanze Jennifer,Chaikin Margery,Manthey Carl L.,Tomczuk Bruce E.,Marugán Juan José

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference45 articles.

1. A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo.

2. Rapid Inhibition of Thyroxine-Induced Bone Resorption in the Rat by an Orally Active Vitronectin Receptor Antagonist

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