Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators-Reference-Cited by-同舟云学术

Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators

Published:2019-10 Issue: Volume:180 Page:253-267
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Hassan Ahmed H.E.^ORCID,Yoo Sung Yeun,Lee Kun Won,Yoon Yoon Mi,Ryu Hye Won,Jeong Youngdo,Shin Ji-Sun,Kang Shin-Young,Kim Seo-Yeon,Lee Hwi-Ho,Park Boyoung Y.,Lee Kyung-Tae,Lee Yong Sup

Funder

National Research Foundation of Korea

Ministry of Education, Science and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference105 articles.

1. Drug repositioning: identifying and developing new uses for existing drugs;Ashburn;Nat. Rev. Drug Discov.,2004

2. NCATS launches drug repurposing program;Allison;Nat. Biotechnol.,2012

3. EGFR inhibitors from cancer to inflammation: discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor;Elkamhawy;Bioorg. Chem.,2019

4. Repositioning of the antipsychotic trifluoperazine: synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents;Kang;Eur. J. Med. Chem.,2018

5. See, cancer risk in patients with inflammatory systemic autoimmune rheumatic diseases: a nationwide population-based dynamic cohort study in Taiwan;Yu;Medicine,2016

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