Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position-Reference-Cited by-同舟云学术

Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position

Published:2019-06 Issue: Volume:171 Page:401-419
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Gálvez José A.,Clavería-Gimeno Rafael,Galano-Frutos Juan J.,Sancho Javier,Velázquez-Campoy Adrian,Abian Olga,Díaz-de-Villegas María D.

Funder

Instituto de Salud Carlos III

European Union

Instituto de la Salud Carlos III

Gobierno de Aragón-FSE

Centro de Investigacion Biomédica en Red en Enfermedades Hepaticas y Digestivas

Asociación Española de Gastroenterologia

MINECO, Spain

E45_17R

FPU

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference59 articles.

1. Global epidemiology of hepatitis C virus infection: an up-date of the distribution and circulation of hepatitis C virus genotypes;Petruzziello;World J. Gastroenterol.,2016

2. Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study;Lancet Gastroenterol. Hepatol.,2017

3. Liver injury and disease pathogenesis in chronic hepatitis C;Yamane;Curr. Top. Microbiol. Immunol.,2013

4. How do persistent infections with hepatitis C virus cause liver cancer?;Mitchell;Curr. Opin. Virol.,2015

5. Hepatitis C virus infection;Manns;Nat. Rev. Dis. Prim.,2017

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