Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)-Reference-Cited by-同舟云学术

Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

Published:2017-09 Issue: Volume:138 Page:661-668
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Cingolani Gino,Panella Andrea,Perrone Maria Grazia,Vitale Paola,Di Mauro Giuseppe,Fortuna Cosimo G.,Armen Roger S.,Ferorelli Savina,Smith William L.,Scilimati Antonio^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

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3. Cyclooxygenase: structural, cellular, and molecular biology;Smith;Annu. Rev. Biochem.,2000

4. Selective COX-1 inhibition: a therapeutic target to be reconsidered;Perrone;Curr. Med. Chem.,2010

5. Update on SAR studies toward new COX-1 selective inhibitors;Vitale;Curr. Med. Chem.,2015

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