Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity-Reference-Cited by-同舟云学术

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Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity

Published:2018-09 Issue: Volume:157 Page:1005-1016
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Kumar Kunal,Man-Un Ung Peter,Wang Peng,Wang Hui,Li Hailing,Andrews Mary K.,Stewart Andrew F.,Schlessinger Avner,DeVita Robert J.

Funder

NIH

NIDDK

JDRF

Icahn School of Medicine

Swiss National Science Foundation

Dartmouth University

NIH/NIDDK

Diabetes Research Center

Human Islet Research Network

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference70 articles.

1. Activation, regulation, and inhibition of DYRK1A;Becker;FEBS J.,2011

2. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs;Lochhead;Cell (Cambridge, MA, U. S.),2005

3. Mechanism of dual specificity kinase activity of DYRK1A;Walte;FEBS J.,2013

4. DYRK1A: a potential drug target for multiple Down syndrome neuropathologies;Becker;CNS Neurol. Disord. - Drug Targets,2014

5. The role of DYRK1A in neurodegenerative diseases;Wegiel;FEBS J.,2011

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3. EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model;European Journal of Medicinal Chemistry;2024-02

4. Design, Synthesis, and Biological Evaluation of Β-Carboline-Cinnamic Acid Derivatives as Dyrk1a Inhibitors in the Treatment of Diabetes;2024

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