Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells-Reference-Cited by-同舟云学术

Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells

Published:2022-06 Issue: Volume:236 Page:114327
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Feng Xuexin,Yan Ziqin,Zhou Feilong,Lou Jianfeng,Lyu Xilin,Ren Xuelian,Zeng Ziyu,Liu Chenglong,Zhang Shiyan,Zhu Di,Huang He,Yang Jinming,Zhao Yujun^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference51 articles.

1. Hot-spots of Mcl-1 protein;Denis;J. Med. Chem.,2020

2. From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors;Ashkenazi;Nat. Rev. Drug Discov.,2017

3. Multiple functions of BCL-2 family proteins;Hardwick;Cold Spring Harbor Perspect. Biol.,2013

4. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function;Chen;Mol. Cell,2005

5. Structural plasticity underpins promiscuous binding of the prosurvival protein A1;Smits;Structure,2008

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