New peptidomimetic rhodesain inhibitors with improved selectivity towards human cathepsins
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference43 articles.
1. Papain-like cysteine proteases;Brömme;Curr. Protoc. Protein Sci.,2000
2. Papain-like peptidases: structure, function, and evolution;Novinec;Biomol. Concepts,2013
3. Structure, interdomain dynamics and PH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from african trypanosomes;Johé;J. Biol. Chem.,2021
4. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies;Bauer;Drug Discov. Today,2015
5. Drug discovery for a new generation of covalent drugs;Kalgutkar;Expet Opin. Drug Discov.,2012
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