Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease-Reference-Cited by-同舟云学术

Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease

Published:2021-01 Issue: Volume:210 Page:113059
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Toublet François-Xavier^ORCID,Lalut Julien^ORCID,Hatat Bérénice,Lecoutey Cédric^ORCID,Davis Audrey^ORCID,Since Marc^ORCID,Corvaisier Sophie,Freret Thomas^ORCID,Sopková-de Oliveira Santos Jana^ORCID,Claeysen Sylvie^ORCID,Boulouard Michel^ORCID,Dallemagne Patrick^ORCID,Rochais Christophe^ORCID

Funder

Fondation Plan Alzheimer

Fondation Vaincre Alzheimer

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference58 articles.

1. Development of multifunctional molecules as potential therapeutic candidates for Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis in the last decade;Savelieff;Chem. Rev.,2019

2. Rivastigmine for Alzheimer’s disease;Birks;Cochrane Database Syst. Rev.,2009

3. Revisiting the cholinergic hypothesis in the development of Alzheimer’s disease;Craig;Neurosci. Biobehav. Rev.,2011

4. Cholinergic function and Alzheimer’s disease;Giacobini;Int. J. Geriatr. Psychiatr.,2003

5. Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent;Greig;Proc. Natl. Acad. Sci. Unit. States Am.,2005

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New insights into butyrylcholinesterase: Pharmaceutical applications, selective inhibitors and multitarget-directed ligands;European Journal of Medicinal Chemistry;2024-09

2. An Expanded Narrative Review of Neurotransmitters on Alzheimer’s Disease: The Role of Therapeutic Interventions on Neurotransmission;Molecular Neurobiology;2024-07-16

3. Molecular Transformers: Adaptive Multitarget Ligands for Esterase-Induced Transition from Analgesics to Anesthetics;Journal of Medicinal Chemistry;2024-07-16

4. Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents;Molecules;2024-05-03

5. 31st Annual GP2A Medicinal Chemistry Conference;Drugs and Drug Candidates;2024-02-22