Discovery of a chiral fluorinated azetidin-2-one as a tubulin polymerisation inhibitor with potent antitumour efficacy-Reference-Cited by-同舟云学术

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Discovery of a chiral fluorinated azetidin-2-one as a tubulin polymerisation inhibitor with potent antitumour efficacy

Published:2020-07 Issue: Volume:197 Page:112323
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Tang Hairong,Cheng Jiayi,Liang Yuru,Wang Yang

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference22 articles.

1. Microtubule dynamics as a target in oncology;Risinger;Canc. Treat Rev.,2009

2. Synthesis, evaluation, and mechanism study of novel indole-chalcone derivatives exerting effective antitumor activity through microtubule destabilization in vitro and in vivo;Yan;J. Med. Chem.,2016

3. Molecular mechanism of action of microtubule-stabilizing anticancer agents;Prota;Science,2013

4. Blocking blood flow to solid tumors by destabilizing tubulin: an approach to targeting tumor growth;Pérez-Pérez;J. Med. Chem.,2016

5. An overview of tubulin inhibitors that interact with the colchicine binding site;Lu;Pharm. Res.,2012

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1. Discovery of Novel Diaryl-Substituted Fused Heterocycles Targeting Katanin and Tubulin with Potent Antitumor and Antimultidrug Resistance Efficacy;Journal of Medicinal Chemistry;2024-07-12

2. Structure-based approaches for the design of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d][1,2,3]triazoles as tubulin polymerization inhibitors;European Journal of Medicinal Chemistry;2024-04

3. Design, Synthesis and Mechanistic Study of New Dual Targeting HDAC/Tubulin Inhibitors;Future Medicinal Chemistry;2024-03-22

4. β-C(sp3)−H chlorination of amide derivatives via photoinduced copper charge transfer catalysis;Chinese Chemical Letters;2024-02

5. Discovery of chiral 1,4-diarylazetidin-2-one-based hydroxamic acid derivatives as novel tubulin polymerization inhibitors with histone deacetylase inhibitory activity;Bioorganic & Medicinal Chemistry;2023-09

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