Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives

Author:

Perin Nataša,Rep Valentina,Sović Irena,Juričić Štefica,Selgrad Danijel,Klobučar Marko,Pržulj Nataša,Gupta Chhedi Lal,Malod-Dognin Noël,Pavelić Sandra KraljevićORCID,Hranjec Marijana

Funder

Croatian Science Foundation

European Union (European Regional Development Fund

University of Rijeka

European Regional Development Fund

European Research Council

Serbian Ministry of Education and Science Project

Slovenian Research Agency

Medical Research Council

Arthritis Research UK

British Heart Foundation

Cancer Research UK

Chief Scientist Office

Economic and Social Research Council

Engineering and Physical Sciences Research Council

National Institute for Health Research

National Institute for Social Care and Health Research

Wellcome Trust

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference45 articles.

1. Natural phenanthrenes and their biological activity;Kovács;Phytochemistry,2008

2. Synthesis and biological evaluation of phenanthrenes as cytotoxic agents with pharmacophore modeling and ChemGPS-NP prediction as topo II inhibitors;Lee;PLoS One,2012

3. Cytotoxic and antimicrobial activities of substituted phenanthrenes fromthe roots of Combretum adenogonium Steud Ex A. Rich (Combretaceae);Novatus;J. Intercult. Ethnopharmacol.,2015

4. Three new phenanthrenes, a new stilbenoid isolated from the roots of Stemona tuberosa Lour. and their cytotoxicity;Khamko;Nat. Prod. Res.,2013

5. A novel antimicrobial phenanthrene alkaloid from Bryopyllum pinnatum;Okwu;J. Chem. Pharm. Res.,2011

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