Discovery of novel N-sulfonamide-tetrahydroquinolines as potent retinoic acid receptor-related orphan receptor γt inverse agonists for the treatment of autoimmune diseases-Reference-Cited by-同舟云学术

Discovery of novel N-sulfonamide-tetrahydroquinolines as potent retinoic acid receptor-related orphan receptor γt inverse agonists for the treatment of autoimmune diseases

Published:2020-02 Issue: Volume:187 Page:111984
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sun Nannan,Ma Xiaojun,Zhou Kaifeng,Zhu Chen,Cao Zhonglian,Wang Yonghui^ORCID,Xu Jun,Fu Wei

Funder

National Natural Science Foundation of China

Shanghai Science and Technology Development Funds

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference44 articles.

1. The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes;Jetten;Prog. Nucleic Acid Res. Mol. Biol.,2001

2. RORC2: The master of human Th17 cell programming;Unutmaz;Eur. J. Immunol.,2009

3. Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase;Gomez-Rodriguez;Immunity,2009

4. Targeting IL-17 and TH17 cells in chronic inflammation;Miossec;Nat. Rev. Drug Discov.,2012

5. Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential;Kellner;Ther. Adv. Musculoskelet. Dis.,2013

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