Optimization of the chromone scaffold through QSAR and docking studies: Identification of potent inhibitors of ABCG2

Author:

Roussel Emile,Tran-Nguyen Viet-Khoa,Bouhedjar Khalid,Dems Mohamed Abdesselem,Belaidi Amine,Matougui Brahim,Peres Basile,Azioune Ammar,Renaudet Olivier,Falson Pierre,Boumendjel AhcèneORCID

Funder

Agence Nationale de la Recherche

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference28 articles.

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3. Molecular cloning of CDNAs which are highly overexpressed in mitoxantrone-resistant cells;Miyake;Cancer Res.,1999

4. BCRP/ABCG2 and high-alert medications: biochemical, pharmacokinetic, pharmacogenetic, and clinical implications;Hira;Biochem. Pharmacol.,2018

5. Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein;Valdameri;J. Med. Chem.,2012

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