From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction
Author:
Funder
Russian Federation Government
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference73 articles.
1. Structure and function of carbonic anhydrases;Supuran;Biochem. J.,2016
2. Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?;Alterio;Chem. Rev.,2012
3. Carbonic anhydrase inhibitors and activators for novel therapeutic applications;Supuran;Future Med. Chem.,2011
4. Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides;Supuran;Curr. Pharmaceut. Des.,2008
5. The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents;Supuran;Curr. Pharmaceut. Des.,2008
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies;Bioorganic & Medicinal Chemistry;2023-10
2. Versatile Diazomethane Sulfonamide for Expedited Exploration of Azole‐Based Carbonic Anhydrase Inhibitors via [3+2] Cycloaddition;ChemMedChem;2023-04-12
3. Five-Membered Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors;Molecules;2023-04-04
4. Sulfonamides with Heterocyclic Periphery as Antiviral Agents;Molecules;2022-12-21
5. Castagnoli‐Cushman Reaction of 3‐Aryl Glutaric Acids: A Convenient, Diastereoselective Reaction for 6‐Oxo‐2,4‐diarylpiperidine‐3‐carboxylic Acid Scaffold;ChemistrySelect;2022-01-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3