Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors

Author:

Dong Jinyun,Wang Zengtao,Cui JiahuaORCID,Meng Qingqing,Li Shaoshun

Funder

Interdisciplinary Program of Shanghai Jiao Tong University

Fundamental Research Funds for the Central University

Shanghai Natural Science Fund

Shanghai Science and Technology Innovation Program

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference21 articles.

1. Tumor-specific expression of cytochrome P450 CYP1B1;Murray;Cancer Res.,1997

2. Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells;Nakajima;Toxicol. Lett.,2003

3. Taxifolin inhibits 7,12-Dimethylbenz(a)anthracene-induced breast carcinogenesis by regulating AhR/CYP1A1 signaling pathway;Haque;Pharmacogn. Mag.,2018

4. Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats;Rowlands;J. Nutr.,2001

5. Eugenol inhibit 7,12-dimethylbenz[a]anthracene-induced genotoxicity in MCF-7 cells: bifunctional effects on CYP1 and NAD(P)H: quinone oxidoreductase;Han;FEBS Lett.,2007

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