Design of Novel 2-Phenylquinazolin-4-amines as Selective CYP1B1 Inhibitors for Overcoming Paclitaxel Resistance in A549 Cells-Reference-Cited by-同舟云学术

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Design of Novel 2-Phenylquinazolin-4-amines as Selective CYP1B1 Inhibitors for Overcoming Paclitaxel Resistance in A549 Cells

Published:2024-03-21 Issue:7 Volume:67 Page:5883-5901
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Meixian¹,Yang Fengyuan²,Huang Xinyue³,Cai Jiajing¹,Zhang Yuxin¹,Jia Jianhua¹^ORCID,Qiu Dachuan¹^ORCID

Affiliation:

1. Department of Radiation Medicine, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China

2. School of Pharmaceutical Sciences and Innovative Drug Research Centre, Chongqing University, Chongqing 400016, China

3. College of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400054, China

Funder

National Natural Science Foundation of China

Creative Research Group of CQ University

Science and Technology Research Program of Chongqing Municipal Education Commission

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00164

Reference50 articles.

1. The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis

2. The Cytochrome P450 Superfamily: Biochemistry, Evolution and Drug Metabolism in Humans

3. Cytochrome P450 and Chemical Toxicology

4. Inhibitors and Prodrugs Targeting CYP1: A Novel Approach in Cancer Prevention and Therapy

5. Cytochrome P450 1B1 Overexpression in Cervical Cancers: Cross-sectional Study

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