Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors-Reference-Cited by-同舟云学术

Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors

Published:2013-12 Issue: Volume:70 Page:400-410
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sun Lingyi,Li Jiarong,Bera Hriday,Dolzhenko Anton V.,Chiu Gigi N.C.^ORCID,Chui Wai Keung

Funder

National Medical Research Council

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference24 articles.

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3. Increased sensitivity to the prodrug 5′-deoxy-5-fluorouridine and modulation of 5-fluoro-2′-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase;Patterson;Br. J. Cancer,1995

4. An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA;Emura;Int. J. Mol. Med.,2004

5. The rarity of liver toxicity in patients treated with coumarin (1, 2-benzopyrone);Cox;Hum. Exp. Toxicol.,1989

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