Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction-Reference-Cited by-同舟云学术

Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction

Published:2017-01 Issue: Volume:126 Page:384-407
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Surmiak Ewa,Neochoritis Constantinos G.,Musielak Bogdan,Twarda-Clapa Aleksandra,Kurpiewska Katarzyna,Dubin Grzegorz,Camacho Carlos,Holak Tad A.,Dömling Alexander

Funder

Marie Curie FP7-Reintegration-Grants

European Regional Development

Polish National Centre of Science

National Centre of Science

NIH

Innovative Medicines Initiative

Faculty of Biochemistry, Biophysics and Biotechnology of Jagiellonian University

Ministry of Science and Higher Education

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference30 articles.

1. Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo;Gu;Eur. J. Cancer,2014

2. Awakening guardian angels: drugging the p53 pathway;Brown;Nat. Rev. Cancer,2009

3. Translating p53 into the clinic;Cheok;Nat. Rev. Clin. Oncol.,2011

4. MDM2, MDMX and p53 in oncogenesis and Cancer therapy;Wade;Nat. Rev. Cancer,2013

5. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2;Vassilev;Science,2004

Cited by 32 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein–Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy;Journal of Medicinal Chemistry;2023-12-07

2. A Greener Synthetic Approach to Tetrazoles via Multicomponent Reactions;Current Organocatalysis;2023-09

3. Azole-Pyrimidine Hybrid Anticancer Agents: A Review of Molecular Structure, Structure Activity Relationship, and Molecular Docking;Anti-Cancer Agents in Medicinal Chemistry;2022-08-04

4. Multicomponent Reactions in Medicinal Chemistry;Multicomponent Reactions towards Heterocycles;2021-11-26

5. Norepinephrine transporter analog benzylguanidine-conjugated nanoparticles for the delivery of paclitaxel in neuroblastoma;Nanomedicine;2021-11