Discovery of a new class of bicyclic substituted hydroxyphenylmethanones as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors for the treatment of osteoporosis-Reference-Cited by-同舟云学术

Discovery of a new class of bicyclic substituted hydroxyphenylmethanones as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors for the treatment of osteoporosis

Published:2012-01 Issue: Volume:47 Page:1-17
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wetzel Marie,Gargano Emanuele M.,Hinsberger Stefan,Marchais-Oberwinkler Sandrine,Hartmann Rolf W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference52 articles.

1. Sex steroids and bone;Compston;Physiol. Rev.,2001

2. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group;Liberman;N. Engl. J. Med.,1995

3. Change in bone turnover and hip, non-spine, and vertebral fracture in alendronate-treated women: the fracture intervention trial;Bauer;J. Bone Miner. Res.,2004

4. Alendronate for the treatment of osteoporosis in men;Orwoll;N. Engl. J. Med.,2000

5. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators;Ettinger;JAMA,1999

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